13/09/2011
The genome three-dimensional (3D) organization plays important, yet poorlyunderstood roles in gene regulation. Chromosomes assume multiple distinctconformations in relation to the expression status of resident genes andundergo dramatic alterations in higher order structure through the cellcycle....
22/08/2011
This five full-day intensive course will cover state-of-the-art statistical methods for detection of genetic loci influencing complex traits. Each day will include discussions of analysis theory and hands-on computer exercises, focusing on the Mendel software package.
This course is designed...
08/07/2011
We have investigated in the yeast Saccharomyces cerevisiae the mechanisms by which the Mediator, a 25 subunits complex, stimulates the transcription by RNA polymerase (Pol) II of activated genes. We identified a contact between Pol II and the Mediator in vivo and demonstrated that this contact is...
29/04/2011
On April 28 the CNAG welcomed a group of ambassadors accredited to Madrid. The group toured the facility accompanied by the center staff and learned detailed information about the sequencing and data analysis process.
Previously, the delegation attended a talk given by the General Manager of the...
05/04/2011
dnGASP and RGASP3 are collaborative efforts among researchers to compare and evaluatecutting edge methods and strategies for sequencing data mapping and assembly. Twoeditions of...
09/09/2010
Transcription initiation at promoters requires the assemblyofgeneral transcription factors (GTFs) and RNA polymerase(Pol) II. Recent works have shown that Pol II can also berecruited to, and transcribe distal regulatory regions.   We have analyzed initiation and elongation through genome-...

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