09/09/2010
Transcription initiation at promoters requires the assemblyofgeneral transcription factors (GTFs) and RNA polymerase(Pol) II. Recent works have shown that Pol II can also berecruited to, and transcribe distal regulatory regions.   We have analyzed initiation and elongation through genome-...
18/06/2010
Genome-wide mapping of transcription factor-DNA interactions and chromatin epigenetic marks is essential to understand how the expression of the mammalian genome is controlled during normal life and disease.The human and mouse genomes contain about 30 genes encoding ATP-dependent chromatin...

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