The Comparative Genomic group focuses on the characterization and interpretation of genomic differences in phenotypically different genomes.
Still today, the characterization of genomic variation is not straightforward. Our group has been working with the characterization of SNPs, indels and in particular all kinds of CNVs and repeat elements in a wide variety of organisms, including humans, apes, dogs, plants and fish. Our final goal is to understand the phenotypic impact of all these variants by making use of well defined organisms and the fine scale exploration of all of variants.
To study such effects, the Comparative Genomics group employs computational and evolutionary approaches to analyze whole genome datasets for predicting genomic, epigenetic and expression differences between individuals.